Biotech Penny Stocks

Search for the best biotech penny stocks under $5 that are trading on NASDAQ and NYSE. The biotech stocks under $5 gainers and losers list are updated at the end of each market day helping penny stock traders to find the best biotech stocks under $5 to buy and watch.

Biotech Stocks Under $5

Stocks Under $1 $2 $5 Volume >=0 300,000 500,000

Free Penny Stocks Guide

Top Biotech Stocks Under $5
Last updated Jan 16, 2026

Symbol	Chart	Open	High	Low	Close	Volume	Percent
JAGX		0.85	1.87	0.85	1.43	145156030	88.16%
TLSA		1.59	1.75	1.27	1.65	1433142	14.58%
FATE		1.06	1.22	1.04	1.19	4852572	13.33%
NTRP		3.19	3.44	2.63	3.22	111658	12.20%
VERU		2.41	2.72	2.38	2.70	226138	11.11%
CGEN		2.18	2.38	2.02	2.37	957205	10.75%
KALA		0.61	0.72	0.61	0.66	4326216	8.20%
AEMD		2.63	3.19	2.63	2.93	122684	8.12%
EQ		1.08	1.19	1.06	1.15	486247	7.48%
CUE		0.29	0.31	0.28	0.30	1272501	7.14%
LXRX		1.26	1.41	1.26	1.38	2792873	6.98%
ATOS		0.71	0.71	0.59	0.62	1664721	6.90%
FBIO		3.46	3.79	3.40	3.72	748214	6.59%
HSDT		3.18	3.40	3.10	3.31	185256	6.43%
NDRA		4.41	4.79	4.40	4.76	8028	6.25%
ONCY		1.00	1.08	0.99	1.03	1835217	6.19%
XBIO		2.27	2.49	2.20	2.42	73908	6.14%
IOVA		2.29	2.41	2.22	2.35	21578641	5.86%
CRIS		0.90	1.03	0.90	0.99	551150	5.32%
IRIX		1.35	1.45	1.35	1.42	37181	5.19%
ALDX		4.43	4.74	4.22	4.61	1245971	4.54%
PRQR		1.75	1.75	1.60	1.66	547029	4.40%
DTIL		3.85	4.12	3.77	4.06	163869	4.10%
OTLK		0.53	0.56	0.52	0.54	1929069	3.85%
AKTX		0.27	0.31	0.27	0.28	307963	3.70%
GOSS		2.45	2.64	2.45	2.53	3327428	3.69%
SNGX		1.31	1.43	1.31	1.41	129163	3.68%
SLS		3.91	4.10	3.69	3.99	6767761	3.64%
MBOT		2.12	2.21	2.09	2.16	975972	3.35%
ITRM		0.32	0.35	0.31	0.34	284044	3.03%
MRKR		1.76	1.90	1.76	1.81	218803	2.84%
PULM		2.66	2.69	2.46	2.63	15289	2.73%
ENTX		1.59	1.67	1.55	1.62	108503	2.53%
RDHL		1.24	1.39	1.24	1.35	79830	2.27%
AKBA		1.37	1.41	1.34	1.36	2248949	2.26%
IFRX		1.02	1.06	1.00	1.02	461092	2.00%
PHIO		1.12	1.15	1.11	1.14	122057	1.79%
ALEC		1.80	1.98	1.78	1.85	1028675	1.65%
XBIT		2.55	2.58	2.52	2.57	6731	1.58%
NERV		4.36	4.51	4.21	4.50	24788	1.58%
SCYX		0.65	0.67	0.64	0.65	212359	1.56%
MNOV		1.62	1.65	1.58	1.61	64285	1.26%
SNOA		3.28	3.40	3.21	3.32	7482	1.22%
MGNX		1.70	1.79	1.70	1.73	1248889	1.17%
RMTI		0.95	0.99	0.95	0.96	55314	1.05%

Top Biotech Stock Losers Under $5
Last updated Jan 16, 2026

Symbol	Chart	Open	High	Low	Close	Volume	Percent
ABUS		4.66	4.66	3.68	4.06	7997041	-13.43%
GNPX		3.44	3.49	2.81	3.00	1607844	-8.81%
AGEN		3.75	3.77	3.31	3.36	1527208	-8.70%
CASI		1.07	1.10	0.95	0.95	20341	-7.77%
SGMO		0.45	0.45	0.40	0.40	7093281	-6.98%
PACB		2.36	2.40	2.21	2.21	5554683	-5.96%
PRPH		0.17	0.18	0.14	0.16	228800	-5.88%
CNTX		1.50	1.53	1.42	1.44	1056541	-4.64%
ORGO		3.91	4.00	3.78	3.79	414732	-4.53%
AUTL		1.44	1.46	1.37	1.38	1596110	-4.17%
BTAI		1.96	2.00	1.84	1.84	536730	-4.17%
ACIU		3.65	3.67	3.47	3.50	155392	-3.85%
HOTH		1.07	1.09	1.01	1.05	319295	-3.67%
GALT		3.14	3.14	2.96	3.05	442959	-3.48%
EDIT		2.12	2.16	2.00	2.03	1940579	-3.33%
CHRS		1.66	1.70	1.59	1.61	863279	-3.01%
ESPR		3.15	3.17	3.03	3.04	3685538	-2.88%
IMMP		3.02	3.06	2.90	2.94	101798	-2.65%
ATRA		4.85	5.00	4.52	4.55	424336	-2.15%
MBRX		4.14	4.40	4.06	4.15	115738	-2.12%
RCKT		3.75	3.76	3.52	3.64	2590943	-1.89%
OVID		1.58	1.64	1.57	1.57	705679	-1.88%
ACRS		2.67	2.70	2.61	2.62	583235	-1.87%
AYTU		2.75	2.75	2.64	2.70	137743	-1.82%
SYBX		1.10	1.14	1.10	1.13	3876	-1.74%
VYGR		3.87	3.95	3.72	3.77	398960	-1.57%
DARE		1.98	2.02	1.93	1.93	40503	-1.53%
TRIB		0.69	0.72	0.68	0.70	105038	-1.41%
GLMD		0.78	0.80	0.76	0.78	70112	-1.27%
AQST		3.34	3.42	3.26	3.30	3544823	-1.20%
IRWD		4.53	4.80	4.47	4.49	2130676	-1.10%
ORMP		3.48	3.71	3.37	3.67	288228	-1.08%